POST-DOCTORAL POSITION AT IMAGING OF GENE REGULATION UNIT

IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a Post-doctoral Fellow to join the Imaging of Gene Regulation lab, led by Prof. Davide Mazza.
The Imaging of Gene Regulation lab develops and applies innovative microscopy approaches to dissect in a quantitative manner how gene expression is controlled in living cells. In particular, we have developed intranuclear single molecule tracking approaches that over the last decade have allowed characterizing how transcription factors search for their targets in living cells, and what is the relationship between the factors kinetics and their activity.  The lab is located within the San Raffaele Research Institute, the leading research hospital in Italy, hosting a wide research program that spans from basic to translational and clinical research, and state-of-the art facilities and infrastructures.

Main activities: 

A (renewable) two-year position is available in the Imaging of Gene Regulation lab of San Raffaele Scientific Institute. The project – funded by the Italian Association for Cancer Research, AIRC – aims at characterizing how the dynamics of the tumor suppressor p53 at multiple scales determine the cancer cell response to genotoxic therapies. The selected candidate will use cutting edge technologies, ranging from in-house developed single molecule imaging approaches to gene editing and -omics to determine how p53 recruitment to nuclear substructures can in turn modulate its activity to control cell fate.

Who we are looking for: 

We are seeking enthusiastic candidates – passionate about basic research and interested in working in a highly multidisciplinary, diverse and international environment, with a strong focus on quantitative biology. Previous experience in advanced imaging approaches will be welcome, but it is not needed. The post-doctoral fellow will be exposed to wet-lab and computational/data-analysis, so previous expertise in either aspect will be considered a plus.
Qualifications:
• PhD in Biology, Biotechnology, Biophysics, Bioengineering, Computational Biology, and related fields. 
• Motivation.
• Team-working attitude.
• Problem solving skills; independent thinking.   
• Fluency in written and spoken English.

Interested candidates should submit their application together with a CV, a letter of motivation and contact information of two referees.

Work details: 

• Type of contract: 2-year (renewable) post-doctoral position (Contratto di collaborazione)
• Duration: Two years.
• Place of work: IRCCS San Raffaele Scientific Institute, via Olgettina, 60 - Milan (Italy). 

At San Raffaele Scientific Institute, a world-renowned center of excellence for clinical and scientific activities, we believe that considering diversity and promoting an open and inclusive environment is crucial to our success. We are committed to ensure that equal employment opportunities are provided and based on merit without regard to age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally recognized status entitled to protection under applicable laws. We offer attractive conditions and rewards appropriate to an internationally competitive research organization.